Severe infections in kidney transplanted children

Infections in Transplanted Patients

Solid-organ transplantation is a therapeutic option for many end-stage diseases. One of the most common complications in the post-transplant period are different kind of infections. They are caused by some bacterial pathogens such as Legionella spp., Nocardia spp., Salmonella spp. and Listeria monocytogenes, many viral agents – Cytomegalovirus /CMV/, Herpes simplex virus / HSV/, Varicella-zoste...

Severe Viral Respiratory Tract Infections in Children

A growing transplanted kidney

to thrombectomy and finally to thrombolytic therapy with anticoagulation, which is currently the standard treatment of choice [1]. Here, we present a young woman with bilateral RVT. Her case constituted the first clinical report of heterozygous MTHFR mutation with RVT, which was her only risk factor for the disease. MTHFR is a key enzyme for intracellular folate homeostasis and metabolism that ...

Acute renal failure in the transplanted kidney.

Acute renal failure (ARF) in the transplanted kidney represents a high-stakes area of nephrology and of transplantation practice. A correct diagnosis can lead to rapid return of renal function; an incorrect diagnosis can lead to loss of the graft and severe sequelae for the patient. The diagnostic possibilities are many (Fig. 10-1) and treatments quite different, although the clinical presentat...

Diabetes Mellitus in the Transplanted Kidney

Diabetes mellitus (DM) is the most common cause of chronic kidney disease and end stage renal disease. New onset diabetes mellitus after transplant (NODAT) has been described in approximately 30% of non-diabetic kidney-transplant recipients many years post transplantation. DM in patients with kidney transplantation constitutes a major comorbidity, and has significant impact on the patients and ...